Sinocort Tablet Dosage/Direction for Use

The initial dosage of SINOCORT tablet may vary from 4-16 mg/day in single or divided doses. When satisfactory response is obtained, the initial dosage should be reduced gradually by 2 mg every two to three days until the smallest dosage is achieved which will adequately maintain the patients. The initial dosage should be maintained or adjusted until a satisfactory response is noted. If after a reasonable period of time there is lack of satisfactory clinical response, the corticosteroid should be discontinued and the patient transferred to other appropriate therapy. It should be emphasized that dosage requirements are variable and must be individualized on the basis of the disease under treatment and the response of the patient.
For infants and children, the recommended dosage should be governed by the same considerations rather than by strict adherence to the ratio indicated by age or body weight. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small increments at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached. It should be kept in mind that constant monitoring is needed in regard to drug dosage.
Included in the situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patient's individual drug responsiveness and the effect of patient's exposure to stressful situations. It may be necessary to increase the dosage of SINOCORT for a period of time consistent with the patient's condition. If after long-term therapy the drug is to be stopped, it is recommended that be withdrawn gradually rather than abruptly. Hormone therapy is an adjunct to, and not a replacement for, conventional therapy.
To transfer patients from other corticosteroids: Substitute SINOCORT (Triamcinolone) 4 mg initially in place of each Cortisone 25 mg; Hydrocortisone 20 mg; Prednisone 5 mg; Prednisolone 5 mg; Methylprednisolone 4 mg; Dexamethasone 0.75 mg; Betamethasone 0.6 mg; and Paramethasone 2 mg. Thereafter, dosage should be adjusted according to individual response.